Introduction to Using Cannabis for Autism

by | Jul 24, 2017 | Pediatric

In the Autism Parent community, word spreads FAST. If you’ve been paying attention, you’ve surely heard the stories about seemingly miraculous results from a parent who discovered cannabis for their Autism Spectrum Disorder (ASD) child. I’m one of those parents, and can personally vouch for the extremely positive potential of this most controversial herb.

As a Holistic Nurse focused on natural alternatives to pharmaceuticals, residing in a cannabis-legal state (Oregon), learning how best to apply medical cannabis therapy was a logical decision for me. Cannabis quickly became a major life passion, as this amazing plant was integral in saving my ASD teen daughter from out-of-home placement.

I thought of doing what many consider unthinkable (foster placement), due to safety concerns when my daughter suffered a major puberty crisis, with high-level behaviors including self-injury, aggressive rages, and property destruction. I can attest: there’s nothing more helpless than watching your child suffer to the extent of injuring themselves and others in a blind rage.

The trauma of puberty crisis is experienced by an estimated 50% of Autism families and is, therefore, an exceedingly common presentation during many a child’s coming-of-age1. Having been there myself, I completely empathize and offer hope of resolution upon connecting with kindred ASD parents. After recovering my daughter from her ASD puberty crisis, my resulting passion turned our trauma into purpose: to help other families.

I’ve since personally guided many ASD parents through optimal application of cannabis therapy. For most, it has provided safe and effective relief and eased their family crisis. As a bonus, many using cannabis have successfully weaned off harmful mental health pharmaceutical medications, some of which have permanent side effects (google extra-pyramidal symptoms- not a good scenario).

*Disclaimer: I highly recommend medical oversight for pharmaceutical weaning.*

The only shame of this process is how many parents don’t consider cannabis therapy until every other option to manage their ASD child is completely exhausted. No judgment by the way. It’s lack of education about cannabis that prevents consideration of this safe and effective option.

Now that word is spreading, many parents are using cannabis as a crisis prevention strategy (sometimes well before puberty) and the ASD Biomed treatment adage “the earlier, the better” certainly seems to apply.

I want to be clear that the goal of medical cannabis use for ASD isn’t for parents to get their kids “high” to mellow them out. Instead, the goal is to improve internal balance and optimize function, through individualized microdosing and experimenting to find the “sweet spot” titration. The experimentation process is needed because individual cannabinoid needs vary greatly. With successful medicinal cannabis titration, even with the use of psychotropic components such as THC, a “high” is barely discernible. With successful medicinal cannabis titration, even with the use of psychotropic components such as THC, a “high” is barely discernible. Now for the science supporting cannabis therapy for Autism.

First and Foremost: Endocannabinoid Deficiency Predisposes Autism (2). Read that a few times and let it sink in for a minute. For those who are brand new to the Endocannabinoid system (ECS), think of it as the motherboard that manages the interactions within and between our body’s organ systems. The role of the ECS is homeostasis (maintaining balance) throughout the rest of the body. In response to an imbalance, the ECS will intelligently rebalance what’s out of skew. This includes some important areas for treating ASD such as neurotransmitter balance, immune modulation, and mitigating inflammation (3). In fact, one cause of ASD is genetic Endocannabinoid System receptor mutations which lead to ECS deficiency (4).

The cannabis plant has the most prolific source of phytocannabinoids available to supplement what is lacking in the ECS of those with ASD. This explains why cannabis can have such a profoundly positive impact as an intervention for Autism.
So, how exactly does cannabis benefit one with Autism? Well, let’s start with symptom management. Cannabis is very effective at minimizing or completely stopping extreme Autism behaviors before, during, or after puberty. The anxiolytic (5), pain-relieving (6), and anti-inflammatory (7) effects of cannabis seem to come in particularly handy for managing Autism behaviors.

Also, cannabis is considered very safe with much milder side effects compared to its pharmaceutical alternatives (8). Hence the symptom management piece that is renowned for alleviating harsh situations in ASD families, even when at or near their breaking point.

In addition to its symptom management efficacy, cannabis also promotes a balance of some underlying issues that cause Autism…hence my inclination to call it potentially “curative.” Biomedical ASD 101: Autism is caused by a combination of genetic and environmental impacts that result in pervasive imbalances, predominantly in the gut, brain, and immune systems (9).
When cannabis activates the Endocannabinoid System, the effect includes balancing of all three of these major organ systems gone defunct in ASD. Cannabis is immune modulating (10), neurotransmitter balancing and neuroprotective (11), plus anti-inflammatory to the gut and brain (7,9), to name a few of the profound curative effects.

Cannabis itself has been one of the “big hitters” in recovering my own ASD daughter, who made more progress between the ages of 11-14 (post-cannabis) than in the Biomed-heavy decade prior.

If you have a child with Autism who you believe may benefit from cannabis, but are unsure where to begin, I highly recommend connecting with Mother’s Advocating Medical Marijuana for Autism (MAMMA). I urge you to seriously consider this safe and effective therapy if you have a child with Autism.

For more information about Nurse Janna, please visit her website.


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De Petrocellis, L., Cascio, M. G. and Di Marzo, V. (2004) The endocannabinoid system: a general view and latest additions. British Journal of Pharmacology 141, 765–774.
Dilja, D., Krueger, N. (2013) Evidence for a common endocannabinoid-related pathomechanism in autism spectrum disorders. Neuron: 78(3):408–410.
Blessing, E., Steenkamp, M., Manzanares, J., Marmar, C., (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics: 12(4):825-36.
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Medical Marijuana vs. Traditional Pharmaceuticals (2016). Medicinal Marijuana Association, accessed online at
Caroline, G., Lopes, S., Silva, P., et al. (2011). Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management. European Journal of Pharmacology, 668: S70–S80.
Thomas, W., Klein, L., Newton, C., Larsen, K., et al. (2003). The cannabinoid system and immune modulation. Journal of Leukocyte Biology. 74(4): 486-496.
Hampson, J., Grimald, M., Axelrod, J., Wink, D, (1998). Cannabidiol and tetrahydrocannabinol are neuroprotective antioxidants. National Academy of Medical Sciences, Vol. 95, pp. 8268–8273.

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